Gentamicin Sulfate Powder, a potent broad-spectrum antibiotic, is particularly effective against Gram-negative bacteria like Escherichia coli and Pseudomonas aeruginosa. Its mechanism of action involves inhibiting bacterial protein synthesis, leading to their demise. This antibiotic is commonly employed to combat severe infections such as pneumonia and urinary tract infections.
In complex cases, Gentamicin Sulfate Powder plays a crucial role in combination therapy to prevent the development of bacterial resistance. Its inclusion in treatment regimens is vital for managing severe infections and ensuring the appropriate choice of antibiotics for patients.
In laboratory settings, Gentamicin Sulfate Powder is indispensable for testing bacterial susceptibility, assisting healthcare professionals in making informed treatment decisions. Its ability to guide therapy based on bacterial sensitivity patterns is essential for optimizing patient care and treatment outcomes.
In summary, Gentamicin Sulfate Powder’s broad-spectrum efficacy against a range of bacteria, particularly Gram-negatives, its significance in combination therapy, and its role in susceptibility testing underscore its importance as a crucial tool in the treatment of bacterial infections. Its use is fundamental in managing severe infections and guiding effective antibiotic treatment strategies.
Cat. Number | AS-2030 |
CAS Number | 1405-41-0 |
Additional CAS | 1403-66-3 (base) |
MDL Number | MFCD00270181 |
Pubchem | 310274086 |
Molecular Weight | 575.68 g/mol |
Molecular Formula | C21H43N5O7.H2SO4 |
Storage Temperature | +4°C |
Form and Color | Powder to crystalline powder / white to off-white |
Solubility | Soluble in water / partially soluble in ethanol |
pH value | 3.5 – 5.5 |
Water Content | ≤ 18% |
Activity (anhydrous basis) | ≥ 590 IU/mg |
Gentamycin C1A | 10 – 35 % |
Gentamycin C2 + C2a | 25-55% |
Gentamycin C1 | 25 – 50 % |
Specific Optical Rotation [α] D | 107 - 121 |
Methanol | ≤ 1% |
Sulfate (anhydrous) | 32 – 35 % |
Sulfated Ash | ≤ 1% |
FT-IR Spectrum | Corresponds to spectrum |
Synonym | Garamycin / Gentamicin Sulfate / Gentamicin sulfate salt / Gentiomycin C |