Colistin Sulfate Powder, a polypeptide antibiotic, effectively targets Gram-negative bacteria resistant to other drugs. It disrupts their cell membranes, causing cell death and treating infections like pneumonia and urinary tract infections.
In clinical practice, Colistin Sulfate Powder serves as a last-resort treatment for multidrug-resistant infections, especially in critically ill patients. It’s administered intravenously or through inhalation for lung infections.
Lab settings rely on Colistin Sulfate Powder for susceptibility testing, guiding treatment plans by determining bacterial response to this antibiotic.
Beyond human use, Colistin Sulfate Powder plays a vital role in veterinary medicine, treating bacterial infections in livestock and poultry.
While generally well-tolerated, Colistin Sulfate Powder may cause side effects such as kidney damage and neurotoxicity, requiring careful monitoring during treatment.
Despite its effectiveness, concerns grow over the rise of colistin-resistant bacteria due to widespread usage.
In summary, Colistin Sulfate Powder’s effectiveness against drug-resistant Gram-negative bacteria, its role in severe infections, and significance in veterinary practice underscore its importance in healthcare. Vigilance is necessary due to potential side effects and the emergence of resistant strains.
| Cat. Number | AS-2029 |
| CAS Number | 1264-72-8 |
| MDL Number | MFCD00146495 |
| Pubchem | 310270455 |
| Molecular Weight | 1266.73 g/mol |
| Molecular Formula | C53H102N16O17S |
| Storage Temperature | +4°C |
| Form and Color | Powder to Crystalline powder / White to off-white to pale yellow |
| Purity (HPLC – sum of Polymyxins) | ≥ 77% |
| Potency | ≥ 19000 U/mg (dried basis) |
| pH (1% solution) | 4 - 6 |
| Sulphated Ash | ≤ 1% |
| Water Content | ≤ 15% |
| 1H-NMR Spectrum | Corresponds to assigned spectrum |
| Synonym | Polymyxin E |
