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Cycloheximide

Cycloheximide is a strong inhibitor of protein synthesis which works on eukaryotic cells’ ribosomes.

Category
Catalog Number: AS-2038
CAS Number: 66-81-9
MW: 281.35 gr/mol
MF: C15H23NO4

cycloheximide is a strong inhibitor of protein synthesis which works on eukaryotic cells’ ribosomes. By attaching itself to the 60S ribosomal subunit in eukaryotic cells, it prevents the growth of fungi. While some bacteria possess natural resistance, cycloheximide is not typically used for selective bacterial inhibition in culture media.

Cat. NumberAS-2038
CAS Number66-81-9
MDL NumberMFCD00082346
PubChem310270664
Molecular Weight281.35 gr/mol
Molecular FormulaC15H23NO4
Storage Temperature+4 °C
Form and ColorCrystalline Powder, White or Off-White
IdentificationHPLC
SolubilitySoluble in chloroform, methanol and ethanol
Melting Point112.0 – 121.0 °C
Specific Optical Rotation-26 – -32 °
Impurities≤ 2.0%
Residue on Ignition≤ 0.2%
Water≤ 0.3%
Potency≥ 970μg/mg
Purity≥ 98.0% (HPLC)

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