Amikacin Sulfate Powder
Aminoglycoside, Inhibitor of protein synthesis
- Description
- Product Information
A potent, broad-spectrum aminoglycoside antibiotic that is commonly utilized in microbiology is amikacin sulfate powder. It is useful for cultivating and isolating bacteria.
Amikacin is highly effective against a wide range of bacteria, including both Gram-positive and Gram-negative species (such Staphylococcus aureus and Pseudomonas, E. coli, and Klebsiella). It also actives against bacteria resistant to penicillin and cephalosporins.
Amikacin is an inhibitor of protein synthesis in bacteria. It does this by binding itself to the bacterial ribosome’s 30S subunit. An essential component of cells, the ribosome is responsible for synthesis proteins according to the genetic code. Amikacin interferes with the reading of the genetic code by binding to the 30S subunit. Errors in protein synthesis, like premature termination or incorrect amino acid insertion, may result from this. In the end, this prevents bacterial growth and may cause cell death.
| Cat. Number | AS-2001 |
| CAS Number | 39831-55-5 |
| Additional CAS | 149022-22-0 |
| MDL Number | MFCD00167475 |
| Pubchem | 310266130 |
| Molecular Weight | 781.77 g/mol |
| Molecular Formula | C22H43N5O13.2H2SO4 |
| Storage Temperature | 4°C |
| Form and Color | White, powder to crystalline powder |
| Assay (on dry basis) | 674 to 786 USP U/mg |
| pH | 2 – 4 |
| Loss on Drying | max. 13.0 % |
| FT-IR Spectrum | corresponds to reference spectrum |
| Synonym | O-3-Amino-3-deoxy-a-D-glucopyranosyl-(1→6)-O-[6-amino-6-deoxy-a-D-glucopyranosyl-(1→4)]-N1-[(2S)-4-amino-2-hydroxy-1-oxobutyl]-2-deo xy-D-streptamine sulfate |
| Synonym | 1-N-[L-(-)-gamma-Amino-a-hydroxybutyryl] kanamycin A sulfate |
| Synonym | Amiglyde V |
| Synonym | Amikacin disulfate salt |





















