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Amphotericin B Powder

A macrocycle antibiotic, active against fungi

SKU AS-2002 Category
Catalog Number: AS-2002
CAS Number: 1397-89-3
MW: 924.10 g/mol
MF: 924.10 g/mol

Amphotericin B is a strong antifungal agent. Since it has activity against a variety of fungal strains, it finds uses in microbiology research. This antifungal is an amphipathic fermentation product of the Gram-positive Streptomyces nodosus bacteria. Amphotericin B is a member of the polyene antifungal class.
These polyene antifungals work by targeting ergosterol, which is an essential part of the cell membrane of fungi. When amphotericin B binds to ergosterol, pores in the membrane are created. Crucial ions leak out of these pores, which leads to in the death of fungal cells.

Cat. NumberAS-2002
CAS Number1397-89-3
MDL NumberMFCD00877763
Molecular Weight924.10 g/mol
Molecular FormulaC47H73NO17
Storage Temperature4°C
Form and ColorPowder, Yellow to Orange
Assay (on dry basis)min. 750 IU/mg
Loss on Dryingmax. 5.0 %
FT-IR Spectrumcorresponds to reference spectrum

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