Geneticin Disulfate (G418) Powder is a valuable antibiotic widely used in microbiology for its efficacy against bacterial and fungal infections. This compound, derived from the bacterium Micromonospora rhodorangea, inhibits protein synthesis in both prokaryotic and eukaryotic cells.
In microbiological laboratories, Geneticin Disulfate (G418) Powder is vital for creating selective culture media. These media suppress the growth of bacteria and fungi while allowing the growth of genetically modified cells. Microbiologists rely on Geneticin Disulfate (G418) Powder’s broad-spectrum activity to study and identify various microbial strains, gaining critical insights into their characteristics.
Moreover, Geneticin Disulfate (G418) Powder is essential for cell culture work, especially in selecting and maintaining genetically engineered cells. Its mechanism of action involves preventing elongation during protein synthesis, making it a valuable tool in genetic engineering experiments.
Additionally, researchers frequently use Geneticin Disulfate (G418) Powder to study gene expression and protein production. By introducing this antibiotic into cell cultures, scientists can select cells with integrated genetic constructs and monitor their expression levels.
Cat. Number | AS-2011 |
CAS Number | 108321-42-2 |
Additional CAS | 49863-47-0 |
MDL Number | MFCD00058314 |
Pubchem | 310274067 |
Molecular Weight | 692.71 g/mol |
Molecular Formula | C20H44N4O18S2 |
Storage Temperature | 4°C |
Form and Color | Crystalline powder, white to off-white |
Solubility (10% in water) | Clear |
Potency (dried basis) | ≥ 720 µg/mg |
pH (20% in water) | 4.6 – 6% |
Water content | Max. 14% |
Ammonia | ≤ 0.5% |